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Name Checker

Please insert a variant description using the HGVS format.

Examples: AB026906.1:c.40_42del, NG_012337.1(SDHD_v001):c.274G>T, LRG_24t1:c.159dup


0 Errors, 0 Warnings.


Overview of the raw variants

Raw variant 1: substitution at 219

AAACTTGTGGTAGTTGGAGCTGGTG G CGTAGGCAAGAGTGCCTTGACGATA
AAACTTGTGGTAGTTGGAGCTGGTG A CGTAGGCAAGAGTGCCTTGACGATA

View original variant in UCSC Genome Browser

Description relative to transcription start

(Not for use in LSDBs in case of protein-coding transcripts).

NM_004985.3:n.219G>A

Affected transcripts - 1

Affected proteins - 1

NM_004985.3(KRAS_i001):p.(Gly13Asp)

Reference protein

  1  MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG
61 QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL
121 PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK
181 SKTKCVIM*

Protein predicted from variant coding sequence

  1  MTEYKLVVVG AGDVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG
61 QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL
121 PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK
181 SKTKCVIM*

Effects on Restriction sites

Raw variant Created Deleted
1 HphI, HpyCH4IV, Tsp45I

Experimental services

Genomic description: 219G>A

Exon information

Number Start (g.) Stop (g.) Start (c.) Stop (c.)
1 182 748 1 567

CDS information

g. c.
Start 182 1
Stop 748 567

Links

Download this reference sequence file: NM_004985.3.gb


Name ID Locus tag Product Link method
KRAS_v001 NM_004985.3 construction
KRAS_i001 NP_004976.2 GTPase KRas isoform b precursor construction

Link methods priorities order: protein (NCBI), locus tag, product tag, exhaustion, and construction.